UC Davis to House New National Biophotonics Center
Projects Already in the Works

Inside the handheld pathogen detector device created with Biophotonic technology, an antigen bead emits a specialized light created with an antibody that will attach to harmful pathogens. Animation still by Steve Oerding, IET Mediaworks
The sci-fi dream of using laser and light scanners to examine and treat medical patients is moving closer to reality, as UC Davis recently announced the creation of the Center for Biophotonics Science and Technology. Funded with $52 million over the next 10 years, including a $40 million grant from the National Science Foundation (NSF), this new center will facilitate collaboration across disciplines and provide equipment and lab space for scientists as they develop new biophotonics applications and techniques. To demonstrate this new center's promise, scientists worked with IET Mediaworks to prepare animations and video footage of a few current examples of their work, including a portable pathogen detector that will be used to quickly identify potentially deadly viruses and other biological agents.

What Is Biophotonics?
Previous Issues
  • IT Times Diverse Campus Team Aces Bid for Biophotonics Center: Mediaworks Plays Integral Role

  • UC Davis Center for Biophotonics

  • Biophotonics International

  • Mediaworks

  • Introduction to Biophotonics

  • National Science Foundation

  • Biophotonics, the science of generating and harnessing light photons to image, detect, and manipulate biological materials, offers the ability to diagnose and monitor disease nearly at the speed of light, based on light and laser interactions with human tissue. Biophotonics will allow healthcare professionals to learn in moments what before took hours or days to diagnose. Future uses of this technology will speed up treatment commencement and severely minimize, and in some cases virtually eliminate, the hospital time and long recovery periods that current procedures require.

    "Lasers have become an essential element in clinical practice in contemporary medicine and surgery," said James E. Boggan, professor of neurological surgery at UC Davis School of Medicine and Medical Center and co-director of the new center.

    Biophotonics also allows for studying human tissue at the cellular and molecular level to detect, diagnose and monitor disease. At the UC Davis Medical Center, biophotonic technology is being utilized in an experimental device that recently started clinical trials for taking biopsies in women for breast cancer. If this trial is successful, it may eliminate the radical Lumpectomy procedure that is used now to take a tissue sample from the breast. Other applications of this technology include the non-invasive early detection of diabetes and cervical cancer (for more information, see http://biophotonics.ucdavis.edu/).

    UC Davis Comes Out on Top
    Recognizing the revolutionary impact of biophotonics, over 150 different academic institutions applied for the $40 million grant that the NSF awarded to UC Davis. (To read more about UC Davis bid for the grant made last October see the December 2001 IT Times story at http://ittimes.ucdavis.edu/dec2001/biophotonics.html).

    The new center will bring together roughly 100 researchers, including physical scientists, life scientists, physicians and engineers and other members from Universities all over the country.

    According to campus officials, this extensive collaboration between UC Davis and other universities is a reflection of the campus' history of researchers from different fields working together. "To be selected as the lead campus for such a major multidisciplinary center is a tribute to the strength and depth of UC Davis' research, especially in areas such as biophotonics that cross boundaries between disciplines," said Virginia Hinshaw, provost and executive vice chancellor at UC Davis.

    Work is Already Underway
    Physicians and scientists at UC Davis and Lawrence Livermore National Labratory are already testing new microscopes that can more clearly distinguish cancerous and healthy tissue. Plans are underway to develop a hand-held pathogen detection unit to quickly identify the presence of potentially infectious agents, from anthrax to smallpox. In fact, test versions of this unit will be used by United Nations inspectors in Iraq to help detect the presence of biological weapons.

    Mediaworks Helps Center Unveil Projects to the Public
    To further demonstrate the possibilities of biophotonics in devices like the pathogen detector, scientists worked with Mediaworks, the campus instructional technology and digital media service, to create a series of animations and video clips. The animation and b-roll footage were used during the press conference announcing the Center, and is now available on the Center's Web site (http://biophotonics.ucdavis.edu/news/video/). "The video animations provided by Steve Oerding and other artists were extremely well-done, and clearly demonstrated what can be extremely complex technical topics," says Leslie Sandberg, Chief Information Officer for the Center.
    Oerding worked with scientists to create a model of the pathogen detector device. Image by Steve Oerding, IET Mediaworks

    Oerding worked under unusual circumstances to create the animations. Since the nature of the new device is highly classified, Oerding had to communicate by phone only with the scientist, who was at an undisclosed location. The inventor could only provide a faxed rough sketch of the yet-to-be-created pathogen detector, also sending along a PowerPoint presentation describing the functionality of the device. From there, Oerding created a sketch, then a pen/ink drawing, scanned the images and brought them into Photoshop. After that, he used Adobe After Effects where he could fully animate the illustrations. Other folks at Mediaworks supplied the sound, music and a voice-over that Oerding added to the press demonstration video.

    "It was interesting working on such a high-profile government project," Oerding explains. "The outcome of this work will be much more high profile than most of my work here on campus," says Oerding, a Mediaworks artist whose job often consists of supporting professors, scientists, or staff by supplying them with various formats of media for their educational projects. "This pathogen detector will be used by first responders in many branches of the United States government to detect biological attacks," he remarks.

    Future Plans Include Educating Students
    According to Sandberg, a major thrust of the new Center will be to spark an interest in science in children and young adults so that they can become tomorrow's science and technology leaders.

    To achieve those aims, the Center will partner with schools and universities of all levels, from elementary to the collegiate level. UC Davis will also develop undergraduate and graduate courses in biophotonics, including a new mentoring program called "shadow a scientist." The Center also will work with minorities and women to ensure that the next generation of scientists is a diverse group.

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